K. Desloovere, J. De Cat a,b, G. Molenaers, I. Franki, E. Himpens,H. Van Waelvelde, K. Fagard, C. Van den Broeck
Aim: To distinguish the effects of different physiotherapeutic programs in a post BTX-A
regime for children with Cerebral Palsy (CP).
Design: Retrospective, controlled intervention study.
Participants and interventions: A group of 38 children (X ¼ 7y7m, GMFCS I-III, 27 bilateral, 11
unilateral CP) receiving an individually defined Neurodevelopment Treatment (NDT)
program, was matched and compared to a group of children with the same age, GMFCS and
diagnosis, receiving more conventional physiotherapy treatment. All patients received
selective tone-reduction by means of multilevel BTX-A injections and adequate follow-up
treatment, including physiotherapy.
Outcome measures: Three-dimensional gait analyses and clinical examination was performed
pre and two months post-injection. Treatment success was defined using the Goal
Attainment Scale (GAS).
Results: Both groups’ mean converted GAS scores were above 50. The average converted
GAS score was higher in the group of children receiving NDT than in the group receiving
conventional physiotherapy ( p < 0.05). In the NDT group, overall treatment success was
achieved in 76% of the goals, compared to 67% of the goals defined for the conventional
physiotherapy group. Especially for the goals based on gait analyses ( p < 0.05) and in the
group of children with bilateral CP ( p < 0.05), treatment success was higher in the NDT
Conclusion: In a post-BTX-A regime, the short-term effects of an NDT approach are more
pronouncedthan these from a conventional physiotherapy approach.
europ e an j o u r n a l of p a e d i a t r i c neurology 1 6 ( 2 0 1 2 ) 2 0 e2 8